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. 2022 Dec 27;23:562. doi: 10.1186/s12859-022-05109-8

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Construction and validation of the prognostic model. A Forest plot of the prognostic GTs in LUAD from TCGA cohort by Univariate Cox regression analysis. B 5 GTs identified by multivariate. Cox regression analysis. C KM survival curve of OS of LUAD patients in the TCGA cohort. D ROC curve analysis for measuring the prognostic performance of the signature-based risk score on OS. E Risk score, survival status, and 5 GTs expression heatmap of the LUAD patients in the TCGA cohort. F–H KM survival curve, ROC curve, risk score, survival status, and 5 GTs expression heatmap of LUAD patients in GSE39055 dataset