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. 2022 Dec 26;27:306. doi: 10.1186/s40001-022-00942-2

Table 2.

RBE values carbon ion/proton in prostate cancer cell lines

Author, year RBE model RBE value
Konings 2019 L–Q PC-3: 0.94 (proton) and 1.93 (carbon ion)
Butterworth 2012 Not reported DU-145: 1.1
Khachonkham 2020 L–Q DU-145: 1.28 ± 0.25, 1.37 ± 0.17 and 1.52 ± 0.17 (within SOBP); 1.27 ± 0.27, 0.97 ± 0.4 (before peak)a
Tinganelli 2013 L–Q RAT-1: 2.8 ± 0.2 (oxic) and 3.7 ± 0.1 (anoxic)
Polf 2011 L–Q DU-145: 1.3 (untreated) and 1.5 (Au-treated)
Suetens 2015 L–Q PC-3: 1.67

RBE relative biological effectiveness, L–Q linear–quadratic

a Data were from RBE10, RBE2Gy and RBE4Gy were not shown in this table