TABLE 2.
Statistically significant sequence conservation in binomial test.
| pfamid | Bonf. p | pfam_description | PDB hit's family | PDB hit | Z | %ide |
|---|---|---|---|---|---|---|
| PF03016 | 0.00141 | Exostosin family with glycosyltransferase activities | PF05686 Glycosyltransferase family 90 | 5f84A | 11.7 | 14 |
| PF03690 | 0.0221 | Uncharacterized protein family (UPF0160); DHH motif | PF01368 DHH family phosphoesterase (CL0137) | 6mtzB | 8.3 | 24 |
| PF03942 | 0.00417 | DTW domain | PF04034 RIbosome biogenesis protein, C‐terminal | 5apgA | 9.8 | 21 |
| PF04250 | 0.000649 | Protein of unknown function (DUF429) | PF02075 Crossover junction endodeoxyribonuclease RuvC (CL0219) | 6s16B | 9.5 | 15 |
| PF04293 | 0.00291 | SpoVR like protein | PF05960 Bacterial protein of unknown function (DUF885) | 3o0yA | 13.2 | 14 |
| PF04632 | 1.08 E‐10 | Fusaric acid resistance protein family | PF11744 Aluminum activated malate transporter | 7vq3A | 12.7 | 19 |
| PF06356 | 0.0330 | Protein of unknown function (DUF1064) | PF08722 (CL0236) TnsA‐like endonuclease | 1t0fA | 8.3 | 13 |
| PF07759 | 1.94 E‐07 | Protein of unknown function (DUF1615) | PF01464 Transglycosylase SLT domain (CL0037) | 6cf9A | 12.3 | 18 |
| PF08889 | 7.61 E‐05 | WbqC‐like protein family | PF10079 Bacillithiol biosynthesis BshC | 4wbdA | 12.1 | 12 |
| PF10070 | 9.41 E‐10 | Probable inorganic carbon transporter subunit DabA | PF08936 Carboxysome shell carbonic anhydrase | 2fgyA | 13.5 | 13 |
| PF10307 | 0.00428 | HAD domain family 1 in Swiss Army Knife RNA repair proteins | PNKP1, component of bacterial RNA repair complex | 4xruA | 10.2 | 14 |
| PF11001 | 0.0310 | Protein of unknown function (DUF2841) | PF04873 Ethylene insensitive 3 | 4zdsA | 12.0 | 20 |
| PF11070 | 0.000261 | Protein of unknown function (DUF2871) | PF00115 Cytochrome c and quinol oxidase polypeptide I (CL0714) | 6lh3B | 13.8 | 19 |
| PF11765 | 0.00648 | Hyphally regulated cell wall protein N‐terminal | Adhesin‐like wall protein 3b | 7o9oA | 28.6 | 18 |
| PF11875 | 0.0404 | DnaJ‐like protein C11, C‐terminal | PF02140 Galactose binding lectin domain | 2zx0A | 3.9 | 19 |
| PF11904 | 0.00762 | GPCR‐chaperone. Adjust domain boundaries. | LolA/B superfamily of lipoprotein localization factors (CL0048) | 2zf4F | 4.4 | 15 |
| PF12062 | 0.000201 | Heparan sulfate‐N‐deacetyse | Carbohydrate deacetylase Agd3 | 6nwzA | 18.5 | 20 |
| PF12222 | 1.64 E‐06 | Peptide N‐acetyl‐beta‐D‐glucosaminyl asparaginase amidase A | PF09112, PF09113 Peptide‐N‐glycosidase F (CL0612) | 4r4xA | 18.4 | 17 |
| PF12617 | 0.00701 | Iron–sulfur binding protein C terminal | PF01680 SOR/SNZ family (CL0036) | 4wy0G | 6.8 | 15 |
| PF13258 | 2.41 E‐05 | Domain of unknown function (DUF4049) | Tyrosine protein phosphatase WipA from Legionella | 5n6xA | 15.4 | 16 |
| PF13898 | 0.0374 | Deubiquitinating enzyme MINDY‐3/4, conserved domain | Deubiquitinase | 7bu0A | 3.8 | 9 |
| PF14033 | 0.0350 | Protein of unknown function (DUF4246) | PF13640 2OG‐Fe(i) oxygenase superfamily (CL0029) | 6n1fA | 13.0 | 9 |
| PF14130 | 0.0200 | Cap4 dsDNA endonuclease | N‐terminal endonuclease domain | 6vm6B | 11.8 | 10 |
| PF14646 | 4.99 E‐05 | MYCBP‐associated protein family | PapD‐like domain 7 (cell cycle protein) | 6fviA | 10.8 | 17 |
| PF14923 | 0.0211 | Coiled‐coil protein 142 | PF07393 Exocyst complex component Sec10 (CL0294) | 5h11A | 13.4 | 9 |
| PF14976 | 0.00943 | FAM72 protein | PF03226 Yippe zinc‐binding/DNA‐binding Mis18, centromere assembly (CL0080) | 5hj0C | 10.0 | 13 |
| PF15851 | 0.00453 | Domain of unknown function (DUF4723) | Glycosylphosphatidulinositol‐anchored high density lipoproterin‐binding protein 1 | 6e7kC | 11.1 | 24 |
| PF16062 | 4.79 E‐06 | Domain of unknown function (DUF4804) | Legionella effector protein MavL | 6omiB | 28.6 | 16 |
| PF17659 | 1.69 E‐08 | Family of unknown function (DUF5521) | PF16900 Replication protein A OB domain | 4gnxC | 13.1 | 18 |
| PF17720 | 6.78 E‐07 | Family of unknown function (DUF5565) | PF09414 RNA ligase (CL0078) | 5cotA | 7.3 | 18 |
| PF18168 | 0.0289 | Prim‐pol family 5 | PF01896 DNA primase small subunit (CL0243) | 5l2xA | 10.7 | 15 |
| PF18658 | 0.0274 | Spin‐doc zinc‐finger | PF19088 TUTase nucleotidyltransferase domain | 6iw6A | 4.2 | 14 |
Note: Query family has no structural information in Pfam 35.0; pfamid is hyperlinked to web page visualizing the structural comparison to PDB hit. Protein families of unknown function are highlighted in red.