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. 2023 Jan 1;32(1):e4519. doi: 10.1002/pro.4519

TABLE 3.

Related known functions

Pfamid pfam_description PDB hit's family PDB hit Z %ide Type
PF01548 Transposase PF02075 Crossover junction endodeoxyribonuclease RuvC (CL0219) 4ld0B 11.7 15 E
PF01955 Adenosylcobinamide amidohydrolase PF03576 Peptidase family S58 (CL0635) 5xyoA 11.0 6 E
PF03859 CG‐1 domain PF08549 SWI/SNF and RSC complexes subunit Ssr4 N‐terminal (Holm, 2020) 7k7vA 9.7 25 B
PF04479 RTA1 like protein. 7 transmembrane helices. PF01036 Bacteriorhodopsin‐like protein (CL0192) 1x0k1 13.0 10 T
PF04666 DUF659 Protein of unknown function (transposase‐like proteins with no known function) DNA transposase 2apcA 18.2 14 E
PF04709 Anti‐Mullerian hormone, N terminal region PF00688 TGF‐beta propeptide 6sf2F 6.0 20 B
PF04724 Glycosyltransferase family 17 PF00535 Glycosyl transferase family 2 6e4qA 10.7 10 E
PF04765 Protein of unknown function (DUF616). A number of the members are thought to be glycosyltransferases. PF03414 Glycosyltransferase family 6 2vs3A 10.6 7 E
PF04833 COBRA‐like protein PF00553 Cellulose‐binding domain 6qfsA 8.4 21 B
PF05123 S‐layer like family, N‐terminal region PF07752 S‐layer protein 3u2gA 3.2 12 S
PF05124 S‐layer like family, C‐terminal region PDB protein's sequence assigned to the same Pfam family, but link is missing from pdbmap. 6npsA 6.5 16 S
PF05428 Corticotropin‐releasing factor binding protein (CRF‐BP) PF00431 CUB domain (CL0164). Involved in binding interaction partners. 6fzwD 8.9 21 B
PF05458 Cd27 binding protein (Siva). Zinc finger. PF02318 FYVE‐like zinc finger (CL0390) 2cjsC 6.1 10 B
PF06081 Aromatic acid exporter family member 1 PF06081 Aromatic acid exporter family member 1 7vg3B 13.3 25 T
PF06189 5′‐nucleotidase Polynucleotide kinase 5ujoB 9.6 14 E
PF06420 Mitochondrial genome maintenance MGM101 PF04098 Rad52/22 family double‐strand break repair protein 5xs0G 12.4 16 B
PF06524 NOA36 protein (zinc finger protein 330) PF00643 B‐box zinc finger 6imqA 4.5 17 B
PF07906 ShET2 enterotoxin, N‐terminal region. Is a cysteine protease (Pearson et al., 2017) Ubiquitin‐specific protease (Schlieker et al., 2007) 2j7qA 9.6 8 E
PF07958 Protein of unknown function (DUF1688). Involved in uracil catabolism PF09171 N‐glycosylase/DNA lyase 1xqpA 11.9 12 E
PF09317 Acyl‐CoA dehydrogenase, C‐terminal, bacterial type C‐terminal domain of acyl‐CoA dehydrogenase 3owaA 11.6 12 E
PF10113 FeGP cofactor biosynthesis protein, fibrillarin family PF04055 Radical SAM superfamily (CL0036) 3t7vA 19.8 16 E
PF10238 E2 transcription factor associated phosphoprotein PF03228 Yippee zinc‐binding/DNA‐binding Mis18, centromere assembly 5hj0C 9.2 15 B
PF10337 Putative ER transporter, 6TM, N‐terminal PF11447 Aluminum activated malate transporter 7vojA 16.3 11 T
PF10343 Potential Queuosine, Q, salvage protein family. DNA glycosidase activity has been suggested. PF09171 N‐glycosylase/DNA lyase 1xqoA 12.8 9 E
PF11726 Inovirus Gp2. Involved in viral DNA replication via phospho‐Tyr mechanism. HUH‐endonuclease superfamily 2x3gA 7.8 11 E
PF12141 Beta‐mannosyltransferases PF04041 beta‐1,4‐mannooligosaccharide phosphorylase (CL0143) 3tawA 20.8 11 E
PF14249 Tocopherol cyclase Diels‐Alderase (pericyclase) 7dmnA 21.7 8 E
PF14616 Transcription regulator Rua1, C‐terminal Transcriptional regulator KAISO 2lt7A 3.0 18 B
PF15051 FAM198 protein. UniProt annotates query protein as Golgi associated kinase 1b. PF06702 Golgi casein kinase, C‐terminal, Fam20 5yh3A 18.3 18 E
PF15083 Colipase‐like PF01114 Colipase, N‐terminal domain; PF02740 Colipase, C‐terminal domain (CL0621) 1lpbA 3.2 22 B
PF15704 Mitochondrial ATP synthase subunit Mitochondrial ATP synthase associated protein ASA4 6rdq4 9.0 13 B
PF16094 Proteasome assembly chaperone 4 PF09754 Pac2 family (proteasome assembly chaperone) 3wz2A 17.5 8 B
PF16887 Domain of unknown function (DUF5081). Believed to be involved in type VII secretion system. PF14011 EspG family (secretion‐associated proteins) 4w4lC 11.3 8 T
PF17184 Rit1 N‐terminal domain of tRNA modifying enzyme PF00156 Phosphoribosyltransferase domain (CL0533) 7kl7A 4.4 9 E
PF18143 HAD domain phosphoesterases in Swiss Army Knife RNA repair proteins Inorganic pyrophosphatase, member of the haloacid dehalogenase superfamily (CL0137) 3qu2D 8.2 10 E
PF19043 Nuclear cap binding complex subunit CBP66 PF07065 Cell division cycle protein 123 4zgoA 16.4 14 B
PF19306 Helicase Lhr winged helix domain Winged helix domain of ATP‐dependent DNA helicase (Jones et al., 2018). 5v9xA 14.1 25 B

Note: Query family has no structural information in Pfam 35.0. Type: B, binding; E, enzyme; S, structural; T, transport.