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. 2023 Jan 1;32(1):e4522. doi: 10.1002/pro.4522

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© 2022 The Authors. Protein Science published by Wiley Periodicals LLC on behalf of The Protein Society.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Visualization of RAF1 showing the 14‐3‐3 binding phosphopeptide motif region. Features with no data within this region are turned off. The mutation hotspots can be observed at the top of the figure in the genetic variation section. OMIM disease and cancer‐associated mutations are depicted by green and black boxes, respectively. Functional annotations and structural information are presented in the middle of the figure. Evolutionary conservation scores are shown at the bottom of the figure.