FIGURE 6.

(A) Shows an example of an integrated HP-¹³C research and standard ¹H mpMRI study (patient 1) including key multiparametric T₂-weighted, diffusion, and k_PL images identifying the biopsy target. One ¹H target (PIRADS 4) was identified at right mid-base transition zone and one ¹³C research target (k_PL = 0.0378 s⁻¹) at left mid-apex peripheral zone, as indicated by the arrows. (B) ¹³C and ¹H mpMRI biopsy targets as drawn by an experienced abdominal radiologist. Pathological diagnosis of the tissue sample from the ¹³C target was Gleason 3+3 cancer (16% involvement, 1/2 cores), whereas that from the ¹H-MRI target was described in the histology report as “rare atypical glands”