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(A) Examples of typical influences on the microbiota gut-brain axis including genetics/epigenetics, medications, mode of delivery, lactation, smoking, physical exercise, and environment. (B) Various diseases known to be affected by gut brain axis dysbiosis, including neurodegenerative diseases, cancer, IBD, depression, obesity, pain, and epilepsy. (C) Bidirectional communication mechanisms between the gut and the brain.
