Table 5.

Characteristics of potential proteins ROC curves.

		AUROC	95% CI	Sensitivity	Specificity	P value
HC-SA
	B2M	0.9557	0.9043 to 1.000	0.8919	0.9600	<0.0001
	IGFBP3	0.9232	0.8344 to 1.000	0.9189	0.8800	<0.0001
	IGFALS	0.9805	0.9553 to 1.000	0.9459	0.8000	<0.0001
	APRI	0.9886	0.9668 to 1.000	0.9714	0.9500	<0.0001
	FIB-4	0.9857	0.9589 to 1.000	0.9429	1	<0.0001
	AAR	0.8286	0.7175 to 0.9397	0.7143	0.9545	<0.0001
HC-HSA
	B2M	0.8985	0.7995 to 0.9974	0.8462	0.7200	<0.0001
	IGFBP3	0.6431	0.4189 to 0.8672	0.5385	0.9200	0.1525
	IGFALS	0.5631	0.3749 to 0.7513	0.4615	0.7200	0.5282
	APRI	0.8917	0.7516 to 1.000	0.8333	0.9500	0.0003
	FIB-4	0.8731	0.7403 to 1.000	0.8462	0.8500	0.0004
	AAR	0.5455	0.3090 to 0.7819	0.5000	0.9545	0.6496
SA-NSA
	B2M	0.7131	0.5361 to 0.8901	0.8108	0.6154	0.0234
	IGFBP3	0.8877	0.7972 to 0.9783	0.7027	0.9231	<0.0001
	IGFALS	0.9896	0.9668 to 1.000	1.0000	0.9231	<0.0001
	APRI	0.7952	0.6297 to 0.9608	0.8857	0.6667	0.0025
	FIB-4	0.8813	0.7530 to 1.000	0.9143	0.8462	<0.0001
	AAR	0.7694	0.6160 to 0.9228	0.6571	0.8571	0.0035

NSA, Non-severe ALD; SA, Severe ALD; HC, Health controls.