TABLE 4.

Model predicting mean hippocampal volume in the HTN group at baseline

	Variable	Unstandardized coefficient B	Standardized β	P-value
Main effects	Age	−0.002	−0.37	<0.001
	Sex	0.011	0.18	0.011
	DBP	0.00399	1.50	0.054
Quadratic term	DBP × DBP	−0.000026	−1.55	0.046

Critical value (Eq. [2]): x = −(0.00399/(2 × (−0.000026))) = 77 mmHg.

HTN, hypertension; WML, white matter lesion.