Table 3.
Top 15 GO enrichment terms associated with the downregulated genes.
| Category | Term | Count | P value |
|---|---|---|---|
| BP | Cell adhesion | 26 | 9.09E–10 |
| BP | Extracellular matrix organization | 22 | 6.93E–14 |
| BP | Positive regulation of transcription from RNA polymerase II promoter | 20 | 0.04382 |
| BP | Negative regulation of transcription from RNA polymerase II promoter | 18 | 0.010419 |
| BP | Muscle contraction | 14 | 9.69E–10 |
| CC | Extracellular exosome | 76 | 1.22E–11 |
| CC | Cytosol | 54 | 0.022837 |
| CC | Extracellular space | 52 | 2.83E–13 |
| CC | Extracellular region | 52 | 2.08E–10 |
| CC | Extracellular matrix | 32 | 3.93E–20 |
| MF | Calcium ion binding | 24 | 2.90E–05 |
| MF | Actin binding | 16 | 2.03E–06 |
| MF | Heparin binding | 12 | 4.99E–06 |
| MF | Integrin binding | 11 | 7.08E–07 |
| MF | Structural constituent of muscle | 10 | 1.80E–09 |
BP = biological process, CC = cellular component, GO = Gene Ontology, MF = molecular function, RNA = ribonucleic acid.