Table 2.
Comparison of the biochemical and endocrinological features of the groups.
| Variables | PCOS (n = 43) | Control (n = 47) | P |
|---|---|---|---|
| FBG (mg/dL)* | 89.0 ± 5.8 | 86.0 ± 6.6 | .025 |
| FBI (mU/L)** | 13.8 ± 6.7 | 5.1 ± 3.2 | <.001 |
| HOMA-IR** | 3.1 ± 2.3 | 1.7 ± 0.5 | <.001 |
| HDL-C* | 61.5 ± 7.6 | 64.6 ± 8.1 | .251 |
| TG** | 105.2 ± 54.9 | 102.2 ± 53.1 | .860 |
| LDL-C** | 76.2 ± 31.8 | 62.7 ± 23.4 | .061 |
| TC* | 158.3 ± 37.1 | 146.1 ± 29.4 | .048 |
| LH (U/L)** | 9.8 ± 6.9 | 7.3 ± 6.0 | .036 |
| FSH (U/L)** | 6.5 ± 1.8 | 7.1 ± 1.8 | .096 |
| E2 (pg/mL)** | 39.4 ± 10.0 | 38.5 ± 16.3 | .806 |
| TSH (U/L)** | 2.3 ± 1.0 | 2.2 ± 1.0 | .888 |
| PRL (ng/mL)** | 16.5 ± 9.1 | 15.3 ± 7.2 | .062 |
| DHEAS (mg/dL)** | 370.9 ± 181.1 | 327.1 ± 149.3 | .282 |
| Total-T** | 0.6 ± 0.2 | 0.4 ± 0.2 | <.001 |
| 17OH-P (ng/mL)** | 1.4 ± 1.2 | 1.3 ± 0.7 | .507 |
| CRP (mg/L)** | 3.8 ± 2.5 | 2.9 ± 2.3 | .786 |
| WBC (103/mL)* | 8.7 ± 2.5 | 8.5 ± 2.9 | .903 |
| Neutrophil (%)* | 61.0 ± 9.9 | 61.6 ± 11.6 | .787 |
| Lymphocyte (%)** | 28.5 ± 8.8 | 29.3 ± 9.8 | .928 |
| NLR** | 2.6 ± 1.6 | 2.5 ± 1.3 | .750 |
| Calprotectin (ng/mL)** | 347 ± 28.8 | 188.8 ± 15.3 | .009 |
Data are shown as mean ± SD. Groups were compared using Student’s t test and **Mann-Whitney U test, as appropriate. Statistical significance was defined as P < .05.
17OH-P = 17-hydroxyprogesterone, CRP = serum C-reactive protein, DHEAS = dehydroepiandrosterone sulfate, E2 = estrogen, FBG = fasting blood glucose, FBI = fasting blood insulin, FSH = follicle-stimulating hormone, HDL = high-density lipoprotein, HOMA-IR = homeostatic model assessment of insulin resistance, LDL = low-density lipoprotein, LH = luteinizing hormone, NLR = neutrophil-lymphocyte ratio, PCOS = polycystic ovary syndrome, PRL = prolactin, TC = total cholesterol, TG = triglyceride, total-T = free testosterone, TSH = thyroid-stimulating hormone, WBC = white blood cell.
Student’s t-test.
Mann-Whitney U-test.