Figure 3.
Whole network versus local network dynamics estimation. Scatterplots showing the linear correlation between the τ estimated at the whole network level and the one estimated in a single triode in vitro (i.e., three electrodes placed close to each either in the 16-channels MEA used for in vitro recording, see Materials and Methods), in three different slices (Aa: Pearson correlation = 0.64, p = 0.04; Ba: Pearson correlation = 0.59, p = 0.002; Ca: Pearson correlation = 0.56, p = 0.001). Kernel density estimation (KDE) of in vitro Down durations versus τ estimated at whole network level in the same three slices (Ab, Bb, Cb). KDE of in vitro Down durations versus τ estimated using data from one triode (see scheme above) in the same three slices (Ac, Bc, Cc). KDE of in vitro Down durations versus τ estimated using data from one recording channel (see scheme above) in the same three slices (Ad, Bd, Cd).