TABLE 4.
Secondary outcome.
| Tracheostomy timing | ||||
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| Outcome | ≤4 days | 5–10 days | ≥11 days | P-value |
| In-ICU mortality, no. (%) | 14 (8.6%) a | 35 (8.8%) a | 108 (16.7%) b | <0.001 |
| 30-days mortality, no. (%) | 16 (9.8%) a,b | 41 (10.3%) b | 110 (17%) a | 0.003 |
| Hospital LOS, median (IQR) | 18.7 (12.8–29.5) | 21.7 (15.1–30.2) | 32.1 (24.4–43.8) | <0.001 |
| ICU LOS, median (IQR) | 14.8 (7.7–24.0) | 16.0 (12.1–23.6) | 28.2 (21.7–38.0) | <0.001 |
| Length of MV, median (IQR) | 8.4 (4.2–15.1) | 11.5 (8.6–16.8) | 22.3 (17.1–30.3) | <0.001 |
| MV free days, median (IQR) | 4.6 (2.2–8.8) | 4.1 (1.8–7.1) | 4.2 (1.8–8.5) | 0.414 |
| Sedative days, median (IQR) | 5.0 (3.0–9.0) | 7.0 (4.0–10.0) | 11.0 (6.0–17.0) | <0.001 |
| Analgesia days, median (IQR) | 5.0 (3.0–10.0) | 9.0 (5.0–13.0) | 12.0 (6.0–21.0) | <0.001 |
| Sedation and analgesia free days, median (IQR) | 6.9 (2.1–11.6) | 7.0 (3.5–14.3) | 13.5 (6.4–22.9) | <0.001 |
| VAP rate, n (%) | 15 (9.2) a,b | 49 (12.3) b | 44 (6.8) a | <0.001 |
IQR, interquartile range; MV, mechanical ventilation; LOS, length of stay; VAP, ventilator associated pulmonary. Corner markers a and b represent the results of multiple comparison. In each outcome, the same corner markers mean no statistical difference between the two groups, while different corner markers mean statistical difference between the two groups.