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. 2022 Dec 14;9:1009748. doi: 10.3389/fmed.2022.1009748

TABLE 2.

Total UFH dose per hemodialysis session according to patient characteristics.

Total UFH dose (IU/kg/session) p-value1
Gender Male 126 ± 52 0.7
Female 131 ± 67
Diabetes mellitus Yes 130 ± 51 0.8
No 127 ± 64
CRP ≤5 mg/L 126 ± 58 0.8
>5 mg/L 129 ± 59
Albumin <35 g/dl 136 ± 68 0.5
≥35 g/dl 126 ± 56
Hemoglobin Lowest tertile 125 ± 43 0.96
Middle tertile 129 ± 62
Highest tertile 130 ± 66
Antiplatelet therapy Yes 129 ± 59 0.8
No 126 ± 58
Anticoagulant therapy Yes 137 ± 75 0.5
No 127 ± 55
History of vascular access dysfunction
AVF/AVG Yes (n = 5) 67 ± 13 0.1
No (n = 38) 92 ± 33
Catheter Yes (n = 27) 173 ± 55 0.055
No (n = 29) 145 ± 55

Total UFH dose expressed in IU/kg/session is depicted as mean ± SD.

CRP, c-reactive protein; AVF/AVG, arteriovenous fistula/arteriovenous graft.

1Hypothesis testing of the difference between the different categories of the variable using unpaired t-test (gender, diabetes mellitus, CRP, serum albumin, antiplatelet therapy, anticoagulant therapy, and history of vascular access dysfunction) or one-way anova (hemoglobin tertiles).