Table 4.
Event rates and hazard ratios from Cox proportional hazards model by COVID-19 status 0–4 and ≥5 weeks before surgery in the matched cohort
| Outcomea | Weeks from COVID(+) test to Surgeryb | Total events N (%) |
Hazard ratioc (95% CI) |
|
|---|---|---|---|---|
| All-cause Mortality | COVID-19(−) | 522 (0.40) | REF 1.0 | |
| 0–4 | 74 (0.07) | 2.1 (1.6, 2.7) | ||
| ≥5 | 102 (0.03) | 1.4 (1.1, 1.7) | ||
|
| ||||
| Any Pulmonary Complication | COVID-19(−) | 697 (0.05) | REF 1.0 | |
| 0–4 | 201 (0.19) | 3.4 (2.9, 4.0) | ||
| ≥5 | 249 (0.07) | 1.6 (1.4, 1.9) | ||
|
| ||||
| Any Thrombotic Complication | COVID-19(−) | 645 (0.05) | REF 1.0 | |
| 0–4 | 72 (0.07) | 1.7 (1.3, 2.1) | ||
| ≥5 | 142 (0.04) | 1.2 (1.0, 1.4) | ||
|
| ||||
| Any Septic Complication | COVID-19(−) | 472 (0.03) | REF 1.0 | |
| 0–4 | 108 (0.10) | 2.0 (1.6, 2.5) | ||
| ≥5 | 129 (0.03) | 1.2 (1.0, 1.5) | ||
Abbreviations: CI Confidence Interval; REF The reference group used to calculate all hazard ratios is the COVID(−) group, BMI body mass index; CCI Charlson comorbidity index
Outcomes were observed 3/1/20–3/26/21.Pulmonary complications are a composite of pneumonia, acute respiratory failure, and acute respiratory distress syndrome. Thrombotic complications are a composite of ischemic stroke, myocardial infarction, venous thromboembolism, and arterial thromboembolism. Septic complications are a composite of sepsis from an unspecified source, gram-negative sepsis, and post-procedural septic shock.
Time from COVID-19(+) test to surgery in weeks
Hazard-ratios from Cox-proportional hazards models adjusting for Age, race, sex, anesthesia type, ASA Class, Case urgency, Ethnicity, BMI, CCI