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. Author manuscript; available in PMC: 2024 Jun 1.

Published in final edited form as: Pharm Res. 2022 Jun 28;40(6):1355–1371. doi: 10.1007/s11095-022-03318-7

Table 5:

Rate of deuterium uptake (k) and maximum deuterium uptake (D_max) of the spray-dried and lyophilized samples (n=3).

Formulation	Spray Drying				Lyophilization
	k (h⁻¹)		D_max		k (h⁻¹)		D_max
	Mean	SD	Mean	SD	Mean	SD	Mean	SD
BSA_Pho_Na	0.0285	0.0054	53	4	0.0339	0.0014	59	0
BSA_Pho_K	0.0337	0.0032	81	2	0.0565	0.0052	94	1
BSA_Suc_Na	0.031	0.0045	68	5	0.0369	0.0071	64	4
BSA_Suc_K	0.0454	0.0036	156	2	0.0594	0.0037	143	2
BSA_Cit_Na	0.0194	0.0012	61	0	0.0237	0.0009	68	1
BSA_Cit_K	0.0249	0.0016	67	4	0.0258	0.0034	58	2
BSA_Buffer free	0.0375	0.0047	74	2	0.0492	0.0029	79	1