Table 2.

Blood–Brain Barrier assay of key compounds of benzyloxy chalcones by PAMPA method.

Compounds	Experimental Pe (× 10−6 cm/s)	Prediction
B10	4.93 ± 0.13	CNS +
B15	4.09 ± 0.24	CNS +
Selegiline	5.69 ± 0.04	CNS +

Pe (10⁻⁶ cm/s) > 4.00: CNS + (high permeation); Pe (10⁻⁶ cm/s) < 2.00: CNS − (low permeation ); Pe (10⁻⁶ cm/s) from 2.00 to 4.00: CNS ± (BBB permeation uncertain).