Table 1.
Symptoms | Number of patients with symptom (%) | Female/male |
---|---|---|
Gastrointestinal symptoms and/or weight loss | 47 (72 %) | 15/31***) |
Cognitive dysfunction | 56 (86 %) | 18/37***) |
Psychiatric symptoms | 24 (37 %) | 12/12 |
CNS hyperexcitability (myoclonus, tremor, hyperreflexia seizures) | 49 (75 %) | 13/35***) |
Paresis | 1 (2 %) | 1/0 |
Cerebellar dysfunction | 29 (45 %) | 12/17 |
Brain stem disorders | 16 (25 %) | 5/11 |
Dysautonomia | 19 (29 %) | 5/11****) |
Sleep disorders | 26 (40 %) | 11/15 |
Sensory symptoms (allodynia, pruritus) | 5 (8%) | 0/5 |
Based on the following studies 1, 2, 5–23.
Details given in Supplementary Table S1.
Gender not reported for one patient.
Gender not reported for three patients.