TABLE 2.
Biochemical composition of BAL fluid from lymphocyte-depleted P. carinii-infected mice
| Experimental group | n | Days post inoculation | Dynamic compliancea (% control) | Concn of:
|
Protein/phospholipid ratio (%) | |
|---|---|---|---|---|---|---|
| Phospholipid (mg/ml) | Proteins (μg/ml) | |||||
| C57BL/6 (uninfected) | 3 | 0 | NDb | 0.078 ± 0.004 | 54 ± 1.8 | 70 ± 5.0 |
| C57BL/6 | 5 | 34 | 100 ± 3.0 | 0.087 ± 0.015 | 54 ± 6.0 | 64 ± 4.5 |
| CD4+ and CD8+ depleted | 4 | 34 | 86 ± 6.0 | 0.070 ± 0.005 | 44 ± 8.0 | 63 ± 6.1 |
| CD4+ depleted | 5 | 34 | 49 ± 4.4 | 0.137 ± 0.026c | 167 ± 16c | 126 ± 20c |
a
Dynamic lung compliance data previously reported by Wright et al. (57).
b
ND, measurements not determined for the specific experimental group.
c
P < 0.05 compared to values for both uninfected and infected C57BL/6 control mice and for CD4+- and CD8+-depleted mice.