Table 3. Detailed morphological findings of COVID-19 patients.

*Steatosis: mild (10-33%), moderate (34-66%), and marked (≥67%)

DAD: Diffuse alveolar damage, ASM: Alveolar squamous metaplasia, CA: Corpora amylacea, CZ: Centrizonal, IHC: Immunohistochemistry, MNG: Multinucleated giant cells, NA: Not available, PanZ: Panzonal, Pul. edema: Pulmonary edema, TEM: Transmission electron microscopy, Type II PH: Type II pneumocyte hyperplasia

Patient #	1	2	3	4	5	6	7	8
Lung pathology
DAD, exudative	+	+	+	+	+	NA	+	+
DAD, organizing	+	+	+	-	+	NA	+	+
Septal thickening	-	+	-	-	-	NA	+	+
Other lung pathology	ASM, MNG, Type II PH, Pul edema, macrophage collection	Type II PH, MNG, microthrombi, macrophage collection	Type II PH, MNG, microthrombi, macrophage collection	-	ASM, Type II PH, MNG, macrophage collection	-	Type II PH, MNG, Pul edema, macrophage collection	Type II, PH
Liver findings
Steatosis*	Moderate, CZ	-	Moderate, CZ	Moderate, CZ	Mild, CZ	Mild, CZ	Mild, CZ	Marked, PanZ
Centrizonal necrosis	-	+	-	+	+	-	-	+
Portal pathology	Mild inflammation	Mild inflammation	-	-	-	-	-	Mild inflammation
Other liver pathology	Mild cholestasis, sinusoidal congestion with neutrophils	Sinusoidal microthrombi, sinusoidal congestion with neutrophils, Kupffer cells hyperplasia	Pericellular fibrosis, mild cholestasis	Sinusoidal microthrombi, sinusoidal congestion with neutrophils	Lobular necroinflammation (neutrophilic), sinusoidal congestion with neutrophils	Sinusoidal congestion with neutrophils, kupffer cells hyperplasia	-	Sinusoidal congestion with neutrophils
Brain findings	CA	CA	CA	CA, hypoxic neurons	CA, hypoxic neurons	CA, old healed infarct	CA	CA, hypoxic neurons
SARS-CoV-2 IHC
Lung	+	+	-	-	+	NA	-	+
Liver	-	-	-	-	-	-	-	-
Brain	-	-	-	-	-	-	-	-
TEM (viral particles in the lung)	+	+	-	-	NA	NA	-	+