Table 2.
Hydrogel compositions
| Hydrogel name | PEG-4MAL concentration | RGD concentration | REDV concentration | GPQ-W concentration |
|---|---|---|---|---|
| Hydrogel 1 (PEG1) | 4.0% (w/v) | 2.0 mM | – | 4.9 mM |
| Hydrogel 2 (PEG2) | 5.0% (w/v) | 2.0 mM | – | 6.6 mM |
| Hydrogel 3 (PEG3) | 4.0% (w/v) | 1.0 mM | 1.0 mM | 4.9 mM |
| Hydrogel 4 (PEG4) | 5.0% (w/v) | 1.0 mM | 1.0 mM | 6.6 mM |
| Hydrogel 5 (PEG5) | 4.0% (w/v) | – | 2.0 mM | 4.9 mM |
| Hydrogel 6 (PEG6) | 5.0% (w/v) | – | 2.0 mM | 6.6 mM |
PEG4-MAL hydrogels were tested in 2 different concentrations and 3 different peptide functionalizations using RGD, REDV, or a combination of the two. The concentration of cross-linking peptide GPQ-W was adjusted according to the amount of PEG-4MAL added in the hydrogel.