Fig. 2.

Granuloma number and volume, distribution of granulomas according the evolutionary stages, and number of inflammatory cells in the lungs of control uninfected and Schistosoma mansoni-infected mice untreated and treated with doxycycline hyclate. Groups: Cnt: control uninfected untreated, Sh: infected with S. mansoni, ShD1: infected treated with doxycycline hyclate (5 mg/kg), ShD2: infected treated with doxycycline hyclate (50 mg/kg), ShP: infected treated with praziquantel (Pzt, 200 mg/kg). Data are expressed as mean and standard deviation. The symbols in each group indicate statistical difference (p≤0.05), compared to ∗ Sh and ShD1, # Sh, ShD1 and ShD2, † Cnt.