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. Author manuscript; available in PMC: 2022 Dec 28.
Published in final edited form as: Nat Genet. 2022 Nov 17;54(12):1933–1945. doi: 10.1038/s41588-022-01214-9

Extended Data Fig. 7 |. mdg4 activation renders hosts protection from virus infection.

Extended Data Fig. 7 |

a, By activating mdg4 RNAi from embryonic to adult stage, the survival rates were measured by raising flies on CrPV- or IIV-6-containing food for 20 days. sh-white flies served as controls. b, By activating mdg4 RNAi from embryonic to adult stage, the survival rates were measured after infecting adult files with different viruses with a single meal. c, RT-qPCR to quantify the fold change of DCV mRNA in sh-mdg4 flies at different time points after one-time infection, relative to sh-white controls based on the two-tailed t-test. d, RT-qPCR to quantify the fold change of DCV mRNA in sh-mdg4 flies on day 6 after one-time infection, relative to sh-white controls based on the two-tailed t-test. The bars in panel c and d report mean ± standard deviation for three biological replicates. Comparison of survival curves was completed using a Cox proportional-hazards model for panels a and b.