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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: Clin Exp Med. 2021 May 17;22(1):151–155. doi: 10.1007/s10238-021-00724-w

Table 1.

Eligibility criteria in CAR-T studies treating adults with non-Hodgkin’s lymphoma or B-cell lymphoma (N = 15)

Intervention N (%)
Yescarta (Axicabtagene ciloleucel) 2 (13.3)
Kymriah (Tisagenlecleucel) 1 (6.7)
CD19- or CD20-type CAR-T cell intervention 12 (80.0)
Study type
  Single-arm trial of one intervention 12 (80.0)
Multi-arm trial with multiple doses of same intervention 3 (20.0)
Demographic eligibility criteria
  Specified an age criteria 12 (80.0)
Clinical eligibility criteria
  No comorbidity that would interfere with treatment/assessment 14 (93.3)
  Refractory/prior treatment 13 (86.7)
  Not pregnant/contraception use 10 (66.7)
  CD19 or 20 expression 9 (60.0)
  Given life expectancy 8 (53.3)
  Adequate cognition/understanding of treatment 5 (33.3)
  No prior CAR-T or gene therapy 4 (26.7)
  No prior stem cell transplant 4 (26.7)