Table 2. Internal Cross-Validation Results of the Final CP Models and XGBoost Modelsa.
| model | ROC value | sensitivity | specificity |
|---|---|---|---|
| CP PCM model | 0.762 | 0.773 | 0.750 |
| CP OATP1B1 | 0.773 | 0.777 | 0.769 |
| CP OATP1B3 | 0.800 | 0.833 | 0.767 |
| CP OATP2B1 | 0.664 | 0.726 | 0.602 |
| XGBoost PCM model | 0.903 | 0.916 | 0.702 |
| XGBoost models OATP1B1 | 0.847 | 0.867 | 0.651 |
| XGBoost models OATP1B3 | 0.872 | 0.909 | 0.565 |
| XGBoost models OATP2B1 | 0.764 | 0.799 | 0.627 |
Shown are the 5-fold ROC values and the calculated sensitivity and specificity from the confusion matrix. In each column, the highest value is highlighted in bold.