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. 2022 Dec 27;20:625. doi: 10.1186/s12967-022-03838-1

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — Kaplan–Meier survival curves demonstrate differences in patient outcome groups at a cut-off value by log-rank test for event free survival (EFS) and overall survival (OS). a Tumor volume for EFS; difference was p = 0.064 at a cut-off value of 240.9 cc tumor volume. b ADC-25th percentile^# for EFS; difference was p = 0.0034 at a cut-off value of 1.01. c D-Mean^# for EFS; difference was p = 0.0017 at a cut-off value of 1.11. d D*-Mean^# for EFS; difference was p = 0.0019 at a cut-off value of 27.24. e Metastasis for OS; significant difference was p < 10^–3 by log-rank test. f Tumor volume for OS; the significant difference was p = 0.07 at a cut-off value of 240.9 cc. g D*-Mean^# for OS; difference was p < 10^–3 at a cut-off value of 33.95. h D*.f-skewness^# for OS; difference was p = 0.019 at a cut-off of 3.32. ^# Parameter values were transformed by multiplying with 10³ before analysis