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. 2022 Dec 24;14:1831–1847. doi: 10.2147/IJWH.S366667

Table 2.

Evaluation Overview for the Pregnant Patient with New Onset POTS Symptoms

Evaluation method:
Thorough history
  • symptoms

  • pre-pregnancy symptoms and disorders

  • medications

  • dietary habits

  • fluid intake

  • any other triggers that may be associated with new-onset POTS, such as a viral illness, concussion, or immunization

Physical exam
  • includes a 10-minute stand test with supine and standing blood pressure and heart rate measurements

Cardiovascular and neurologic exams
  • evidence of a heart murmur

  • cardiomegaly

  • pupillary dysfunction

  • loss of temperature and pain sensation in the extremities

Laboratory tests
  • CBC

  • CMP

  • TSH

  • free T4

  • ferritin

  • morning cortisol

  • vitamin B12

  • BNP

  • serum autoimmune panel

  • comprehensive vitamin and nutrient panel

Diagnostic tests
  • EKG

  • 2D cardiac echocardiogram

  • 24-hr Holter monitor

If headache is present:
  • Consider MRI of the brain without contrast if:

    • - Headache is different or new compared to pre-pregnancy headache

    • - Any focal neurologic deficits are present

    • - There is abnormal neurologic exam

  • - Headache is accompanied by blood pressure elevation