TABLE 5.
Determinants of the quality | Overall | Sub analysis | |
---|---|---|---|
SRP + ω‐3 | SRP + ω‐3 and ASA | ||
Study design | RCT | RCT | RCT |
# Experiments (n = 10) | 10 | 8 | 2 |
# Meta‐analysis (n = 10) | 10 | 8 | 2 |
Risk of bias | Low to high | Low | Low to high |
Consistency | Consistent | Consistent | Rather consistent |
Directness | Generalizable | Generalizable | Generalizable |
Precision | Rather precise | Rather precise | Rather precise |
Reporting bias | Possible | Possible | Possible |
Magnitude of the effect (Smiley et al., 2015) | Moderate | Moderate | Moderate |
Strength of the recommendation based on the quality and body of evidence | Moderate | Moderate | Weak |
Overall recommendation | If SRP is indicated, the use of ω‐3 fatty acids can be considered for a moderate extra added effect on PPD reduction and CAL gain | ||
The strength of this recommendation is moderate |
Abbreviations: CAL, clinical attachment level; PPD, probing pocket depth; RCT, randomized controlled trial; SRP, surgical periodontal therapy; ω‐3, omega‐3 fatty acids.