Table 1.
Baseline patient characteristics
| Total (n = 23) | CFRD (n = 6) | Nondiabetic (n = 17) | p value | |
|---|---|---|---|---|
| Age (years) | 17.65 ± 8.2 | 23.1 ± 10.99 | 16.2 ± 5.8 | 0.16 |
| Male (%) | 11 (48%) | 3 (50%) | 8 (47%) | 1.00 |
| PI | 15 (65%) | 4 (66.7%) | 11 (64/7%) | 0.37 |
| BMI (kg/m2) | 19.6 ± 3.4 | 19.3 ± 3.98 | 19.7 ± 3.3 | 0.83 |
| FVC (%) | 85.3 ± 14.02 | 81.33 ± 12.2 | 85.3 ± 14.02 | 0.43 |
| FEV1 (%) | 69.7 ± 18.5 | 58.3 ± 17.6 | 73.7 ± 17.6 | 0.08 |
| FEF25–75 (%) | 51.4 ± 29.5 | 30 ± 14.99 | 58.9 ± 29.9 | 0.035 |
| LCI | 12.6 ± 3.8 | 16.1 ± 4.1 | 11.6 ± 3.1 | 0.013 |
| HbA1C | 5.61 ± 0.59 | 6.2 ± 0.6 | 5.4 ± 0.5 | 0.003 |
| HOMA‐IRa | 2.28 (1.29–2.74) |
Note: Values are presented as mean ± SD.
Abbreviations: BMI, body mass index; CFRD, cystic fibrosis‐related diabetes: FEF25–75, forced expiratory flow between 25% and 75% of FVC; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; HbA1C, hemoglobin A1C; HOMA‐IR, Homeostatic Model Assessment for Insulin Resistance; IQR, interquartile range; LCI, lung clearance index; PI, pancreatic insufficient.
a
Median (IQR).