Table 1.
Associations of mother's and child's ADHD PRS and household chaos with total ADHD, hyperactivity/impulsivity and inattention symptoms from age 5 to age 12
| Model 1, mother and child ADHD PRS | Model 2, household chaos | Model 3, PRS and household chaos | ||||
|---|---|---|---|---|---|---|
| Intercept | Slope | Intercept | Slope | Intercept | Slope | |
| Total ADHD symptoms | IRR | IRR | IRR | IRR | IRR | IRR |
| Mother's ADHD PRS | 1.07 | 0.99 | 1.05 | 0.99 | ||
| Child's ADHD PRS | 1.12** | 1.00 | 1.09* | 1.00 | ||
| Household chaos | 1.47*** | 1.04*** | 1.43*** | 1.04*** | ||
| Hyperactivity/impulsivity | ||||||
| Mother's ADHD PRS | 1.07 | 0.99 | 1.05 | 0.99 | ||
| Child's ADHD PRS | 1.13** | 1.01 | 1.10* | 1.01 | ||
| Household chaos | 1.40*** | 1.05*** | 1.35*** | 1.06*** | ||
| Inattention | ||||||
| Mother's ADHD PRS | 1.06 | 0.99 | 1.02 | 0.99 | ||
| Child's ADHD PRS | 1.12 | 1.00 | 1.09 | 1.00 | ||
| Household chaos | 1.60*** | 1.02** | 1.56*** | 1.02** | ||
*p < .05, **p < .01, ***p < 0.001. IRR, incidence rate ratio; PRS, polygenic risk score. All analyses adjusted for twin intracorrelation and child's sex.