TABLE 3.
Agreement in histopathological results between biopsies and LLETZ
| Cervical biopsy result | LLETZ result | |||
|---|---|---|---|---|
| <CIN2 a | CIN2+ b | Total | ||
| <CIN2 a | 69 (67.6%) | 18 (17.6%) | 87 (85.3%) | |
| CIN2+ b | 0 | 15 (14.7%) | 15 (14.7%) | |
| Total | 69 (67.6%) | 33 (32.4%) | 102 (100%) | |
| Agreement | 84/102 = 82.4% (95% CI 73.6–89.2%) | |||
| Biopsy underestimates disease in all women | 18/102 = 17.6% (95% CI 10.8–26.4%) | |||
| Biopsy underestimates disease in women with CIN2+ detected | 18/33 = 54.5% (95% CI 36.4–71.9%) | |||
| Biopsy overestimates or removes disease | 0/102 (0%) | |||
Abbreviation: CIN, cervical intraepithelial lesion.
a
<CIN2 is defined as: normal or CIN1.
b
CIN2+ is defined as: CIN unclassifiable, CIN grades 2 and 3, and cancer.