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. 2023 Jan;29(1):70–80. doi: 10.3201/eid2901.220975

Table 4. Associations between Corynebacterium diphtheriae carriage and potential risk factors, Vietnam*.

Risk factor Carriage, no. (%)
p value†
Total Tested
Age group, y
<5 12 (4.5) 257 (95.5) <0.01
6‒17 10 (3.1) 314 (96.9)
18‒40 5 (1.0) 518 (99.0)
41‒55
0
102 (100.0)

Sex
M 10 (1.6) 605 (98.4) 0.198
F
17 (2.8)
584 (97.2)

DTP1 <10 years
0 doses 5 (4.5) 107 (95.5) >0.99
>1 dose
16 (4.5)
336 (95.5)

DTP3 <10 years
<3 doses 5 (4.3) 111 (95.7) >0.99
>3 doses
16 (4.6)
332 (95.4)

Diphtheria antibody, IU/mL
<0.1 11 (1.7) 630 (98.3) 0.24
>0.1
16 (2.8)
559 (97.2)

School
Not attended 17 (1.8) 906 (98.2) 0.12
Attended
6 (2.1)
283 (97.9)

Dormitory
Not staying 23 (2.2) 1,035 (97.8) 0.77
Staying
4 (2.5)
154 (97.5)

Sharing bed
Yes 4 (2.7) 143 (97.3) 0.56
No
23 (2.2)
1,037 (97.8)

Household size, no, persons
<4 13 (2.2) 585 (97.8) >0.99
>4
14 (2.3)
604 (97.7)

Bathing, times/day
<1 0 72 (100.0) 0.40
>1
27 (2.4)
1,117 (97.6)

Handwashing, times/day
<3 4 (1.6) 247 (98.4) 0.11
>3
18 (3.9)
445 (96.1)

Livestock or pet animal
No 24 (2.7) 866 (97.3) 0.08
Yes
3 (0.9)
323 (99.1)

Category Positive Negative p value by t-test
MUAC, cm, mean (SD) 15.0 (1.77) 14.8 (1.33) 0.16
Age, y, mean (SD) 7 (9.7) 20 (14.3) <0.01
log-transformed IgG level, mean (SD) ‒1.4 (2.1) ‒2.2 (1.2) <0.01

*DTP, diphtheria‒tetanus‒pertussis; MUAC, mid-upper arm circumference. †By Fisher exact test except as indicated.