TABLE 2.
Laboratory values and percentage of abnormalities in patients at each assessment point
| Biochemical marker (normal range) | Time | N | Minimum | Maximum | Mean ± SD | Abnormalities N (%) |
|---|---|---|---|---|---|---|
| Thiamin pyrophosphatase (TPP) (66–200 nmol/L) | Pre op | 112 | 75 | 445 | 179.6 ± 54.8 | 0 (0.0) |
| ≤6/12 post op | 88 | 48 | 360 | 165.1 ± 51.6 | 2 (2.3) | |
| 1 year post op | 49 | 55 | 340 | 173.5 ± 65.3 | 1 (2.1) | |
| ≥2 years post op | 63 | 65 | 340 | 177.0 ± 56.9 | 0 (0.0) | |
| CRP (0.0–0.5 mg/L) | Pre op | 109 | 0.5 | 48.6 | 7.7 ± 7.3 | 52 (47.7) |
| ≤6/12 post op | 83 | 0.4 | 24.0 | 4.5 ± 4.6 | 21 (25.3) | |
| 1 year post op | 48 | 0.4 | 85.5 | 5.5 ± 12.6 | 6 (12.5) | |
| ≥2 years post op | 62 | 0.4 | 25.7 | 2.5 ± 3.6 | 5 (8.1) | |
| iPTH (1.6–6.9 pmol/L) | Pre op | 105 | 2.0 | 21.1 | 6.8 ± 3.4 | 29 (27.6) |
| ≤6/12 post op | 84 | 2.0 | 10.5 | 5.4 ± 1.9 | 15 (17.9) | |
| 1 year post op | 47 | 2.7 | 35.0 | 6.4 ± 4.8 | 8 (17.0) | |
| ≥2 years post op | 61 | 2.1 | 13.7 | 6.2 ± 2.4 | 14 (23.0) | |
| Albumin (36–47 g/L) | Pre op | 110 | 35.0 | 49.0 | 42.5 ± 2.8 | 2 (1.8) |
| ≤6/12 post op | 87 | 35.0 | 49.0 | 41.7 ± 3.1 | 0 (0.0) | |
| 1 year post op | 49 | 30.0 | 48.0 | 41.9 ± 3.6 | 2 (4.0) | |
| ≥2 years post op | 62 | 35.0 | 50.0 | 41.8 ± 3.2 | 0 (0.0) | |
| Vitamin D (50–140 nmol/L) Total deficiency: <50 nmol/L | Pre op | 107 | 14.0 | 108.0 | 53.1 ± 19.6 |
Total: 42 (39) Mild: 31 (29.0) Moderate: 11 (10.3) Severe: 0 (0.0) |
| Mild deficiency: 30–49 nmol/L | ≤6/12 post op | 86 | 31.0 | 149.0 | 77.5 ± 22.0 | Total: 8 (9.3) |
| Moderate deficiency: 13–29 nmol/L |
Mild: 8 (9.3) Moderate: 0 (0.0) |
|||||
| Severe deficiency: <13 nmol/L | Severe: 0 (0.0) | |||||
| 1 year post op | 47 | 33.0 | 142.0 | 76.5 ± 23.7 |
Total: 5 (10.6) Mild: 5 (10.6) Moderate: 0 (0.0) Severe: 0 (0.0) |
|
| ≥2 years post op | 62 | 16.0 | 253.0 | 68.8 ± 32.3 |
Total: 11 (17.7) Mild: 11 (17.7) Moderate: 0 (0.0) Severe: 0 (0.0) |
|
| Iron (5–30 μmol/L) | Pre op | 112 | 5.9 | 37.0 | 14.7 ± 5.3 | 1 (0.9) |
| ≤6/12 post op | 87 | 9.0 | 117.0 | 18.6 ± 11.8 | 0 (0.0) | |
| 1 year post op | 49 | 3.0 | 28.2 | 17.3 ± 6.0 | 2 (4.1) | |
| ≥2 years post op | 62 | 9.0 | 43.6 | 20.0 ± 6.6 | 0 (0.0) | |
| Ferritin (15–200 μg/L) | Pre op | 110 | 9.0 | 533.0 | 125.3 ± 119.8 |
Low: 14 (12.7) High: 12 (10.9) |
| ≤6/12 post op | 87 | 14.0 | 559.0 | 136.2 ± 112.9 |
Low: 6 (6.9) High: 3 (3.5) |
|
| 1 year post op | 49 | 7.0 | 358.0 | 107.2 ± 81.8 |
Low: 7 (14.3) High: 5 (10.2) |
|
| ≥2 years post op | 63 | 6.0 | 344.0 | 87.7 ± 69.6 |
Low: 10 (15.9) High: 3 (4.8) |
|
| Vitamin B12 (135–650 pmol/L) <250 pmol/L | Pre op | 97 | 150.0 | 1028.0 | 350.9 ± 155.7 | 30 (31.0) |
| ≤6/12 post op | 59 | 148.0 | 1042.0 | 381.8 ± 185.6 | 16 (27.1) | |
| 1 year post op | 42 | 140.0 | 1352.0 | 398.9 ± 228.6 | 8 (19.0) | |
| ≥2 years post op | 56 | 127.0 | 845.0 | 407.3 ± 179.4 | 13 (23.2) | |
| Active B12 * (>35 pmol/L) | Pre op | 87 | 36.0 | 127.0 | 82.3 ± 26.0 | 1 (1.1) |
| ≤6/12 post op | 71 | 24.0 | 124.0 | 65.5 ± 27.3 | 3 (4.2) | |
| 1 year post op | 38 | 33.0 | 127.0 | 71.4 ± 25.3 | 2 (5.3) | |
| ≥2 years post op | 42 | 26.0 | 125.0 | 71.8 ± 29.3 | 4 (9.5) | |
| Folate (>7.0 nmol/L) | Pre op | 111 | 4.5 | 54.0 | 29.4 ± 10.1 | 1 (0.9) |
| ≤6/12 post op | 85 | 6.7 | 53.0 | 26.3 ± 10.2 | 1 (1.2) | |
| 1 year post op | 51 | 6.7 | 54.0 | 29.9 ± 11.1 | 1 (2.0) | |
| ≥2 years post op | 61 | 12.7 | 54.0 | 30.0 ± 9.6 | 1 (1.6) | |
| Total protein (64–83 g/L) | Pre op | 109 | 41.0 | 144.0 | 71.7 ± 8.6 | 3 (2.7) |
| ≤6/12 post op | 84 | 56.0 | 145.0 | 69.6 ± 9.5 | 5 (5.9) | |
| 1 year post op | 49 | 40.0 | 79.0 | 67.5 ± 6.0 | 6 (12.2) | |
| ≥2 years post op | 62 | 57.0 | 79.0 | 67.9 ± 3.7 | 5 (8.1) | |
| Haemoglobin (M) (130–180g/L) | Pre op | 23 | 122.0 | 166.0 | 147.5 ± 13.3 | 1 (4.3) |
| ≤6/12 post op | 12 | 137.0 | 164.0 | 148.3 ± 8.7 | 0 (0.0) | |
| 1 year post op | 8 | 125.0 | 152.0 | 139.1 ± 8.8 | 1 (12.5) | |
| ≥2 years post op | 15 | 129.0 | 172.0 | 147.4 ± 11.5 | 2 (13.3) | |
| Haemoglobin (F) (119–160) | Pre op | 85 | 106.0 | 158.0 | 135.9 ± 9.8 | 3 (3.5) |
| ≤6/12 post op | 74 | 112.0 | 167.0 | 135.5 ± 11.1 | 2 (2.7) | |
| 1 year post op | 43 | 106.0 | 156.0 | 127.5 ± 9.8 | 4 (9.3) | |
| ≥2 years post op | 48 | 113.0 | 159.0 | 134.2 ± 10.3 | 1 (2.1) |
Abbreviations: CRP, C‐reactive protein; F, female; iPTH, intact Parathyroid hormone; M, male.
a
Analysed if vitamin B12 150–250 pmol/L.