FIGURE 2.

Current management of BP‐CML. The flow chart summarises the current approach(es) for management of BP‐CML. Although there are some similarities in management, de novo BP‐CML and progression to BP‐CML on therapy are considered separately. ALL, acute lymphoblastic leukaemia; alloHSCT, allogeneic haemopoietic stem cell transplantation; AML, acute myeloid leukaemia; BP, blast phase; CML, chronic myeloid leukaemia; CNS, central nervous system; CP, chronic phase; DLI, donor lymphocyte infusion; FLAG‐IDA, fludarabine, cytarabine, granulocyte‐colony stimulating factor, idarubicin chemotherapy; lBP, lymphoid blast phase; NGS, next‐generation sequencing; TKI, tyrosine kinase inhibitor.