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. 2022 Jun 28;9(Suppl 2):14–19. doi: 10.33393/grhta.2022.2420

TABLE I -.

Ranking according to the surface under the cumulative ranking curve and mean rank for the efficacy outcomes

Treatment Surface under the cumulative ranking curve Mean rank
Seizure response
Brivaracetam 46.2 3.7
Cenobamate 99.0 1.1
Eslicarbazepine acetate 53.4 3.3
Lacosamide 60.8 3.0
Perampanel 40.7 4.0
Placebo 0.0 6.0
Seizure freedom
Brivaracetam 72.4 2.4
Cenobamate 88.8 1.6
Eslicarbazepine acetate 47.2 3.6
Lacosamide 37.8 4.1
Perampanel 53.0 3.4
Placebo 0.8 6.0

Higher values of surface under the cumulative ranking curve correspond to higher probabilities of better efficacy.