FIGURE 9.

Clinical relevance of kinectome features. (A) The left panel highlights the position of the 10th thoracic vertebra, whose degree in the kinectome derived from the mediolateral accelerations (MLA‐T10) has been analyzed within a clinical framework. The middle panel shows that patients with Parkinson's disease (PD) have significantly higher MLA‐T10 degree with respect to the healthy controls (HC); the right panel shows the positive significant correlation between the MLA‐T10 degree and the clinical motor impairment assessed through the Unified Parkinson's Disease Rating Scale (UPDRS). (B) Multilinear regression model for the prediction of the UPDRS from the MLA‐T10 degree. The left panel shows the explained variance (R ²) of the UPDRS, while sequentially adding the predictors (i.e., age, education, gender, and MLA‐T10 degree) to the model; MLA‐T10 degree was a significant predictor with positive beta coefficient; the middle panel displays the relationship between empirical and predicted UPDRS scores, with k‐fold cross validation (k = 5); and the right panel illustrates the distribution of the residuals with k‐fold cross validation (k = 5).