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Rhodopsin is not required for microvesicle release from rod inner segments. Representative TEM image of a retinal section from a Rho−/− mouse stained with tannic acid/uranyl acetate. Boxed areas in A are magnified in A′ and A″. Arrows point to microvesicles; arrowhead points to a microvesicle in the process of budding from the inner segment. IS, inner segment. OS, outer segment. Scale bars: 0.5 µm. A total of four Rho−/− mice were analyzed.
