Table 2.
Type of biomarker evaluated | Totals, all biomarkers | |||||||
---|---|---|---|---|---|---|---|---|
Characteristic | Genomic | Transcriptomic | Proteomic | Metabolomic | Microbiomic | Cellular | Mixed | |
No. of included studies (% of total) | 41 (23%) | 7 (4%) | 88 (49%) | 8 (4%) | 1 (1%) | 7 (4%) | 29 (16%) | 181 |
Mean/median biomarkers per study | 20/3 | 16/1 | 8/2 | 53/1 | N/A | 3/2 | 9/5 | 13/2 |
Mean/median no. of psoriasis patients | 1305/398 | 76/73 | 235/74 | 89/88 | N/A | 161/96 | 130/72 | 371/92 |
No. of studies evaluated further a (% of studies in category) | 19 (46%) | 2 (29%) | 28 (31%) | 3 (38%) | 0 (0%) | 3 (43%) | 6 (21%) | 61 (34%) |
Candidate biomarkers (% of total) | 10 (45%) | 0 | 10 (45%) | 2 (9%) | 0 | 0 | 0 | 22 |
Studies which were eligible for further data extraction and quality assessment.