FBP54-specific IgG subclass profiles in sera (day 49) of mice immunized with FBP54. Groups I, II, and III correspond to those in Table 1. Values represent the mean ± the SEM of log2 ELISA titers of four or five mice. ND, not detected at an ∼1,000-fold dilution of serum. i.n., intranasal; p.o., peroral.