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. Author manuscript; available in PMC: 2023 Jul 1.
Published in final edited form as: JCSM Rapid Commun. 2022 Jun 20;5(2):254–265. doi: 10.1002/rco2.68

Figure 3. C24, ceramide ratios, and classical circulating factors as biomarkers of cancer cachexia.

Figure 3.

(A) ROC curve for distinguishing non-cachectic from cachectic PDAC patients by C24. (B) ROC curves for distinguishing non-cachectic from cachectic PDAC patients by ratios of sphingolipids (C) ROC curve for C18:C24 distinguishing non-cachectic from cachectic PDAC patients compared to ROC curves for other previously proposed biomarkers of cancer cachexia. ROC curves are displayed as sensitivity vs. (1-specificity) value. n=18 treatment-naïve, non-cachectic PDAC patients, n=35 treatment naïve, cachectic PDAC patients.