. Author manuscript; available in PMC: 2023 Jul 1.

Published in final edited form as: JCSM Rapid Commun. 2022 Jun 20;5(2):254–265. doi: 10.1002/rco2.68

Table 3.

ROC Curve Analysis of Proposed Cachexia Biomarkers

	Non-Cachectic (n=18)	Cachectic (n=35)	AUROC (95% CI)	Optimal Cutoff	p value
C18:C24	0.0933 ± 0.0387	0.201 ± 0.0467	0.810 (0.679–0.921)	>0.055	0.0087
MCP-1 (pg/mL)	290.4 ± 38.9	482.5 ± 57.9	0.660 (0.513–0.797)	>311	0.0410
GDF15 (pg/mL)	1233 ± 235	2097 ± 309	0.671 (0.489–0.800)	>1280	0.0431
Activin (pg/mL)	314.7 ± 48.5	456.7 ± 77.2	0.675 (0.521–0.832)	>386	0.0868
IL-6 (pg/mL)	6.36 ± 2.44	26.47 ± 10.76	0.646 (0.470–0.818)	>1.6	0.1259
Myostatin (pg/mL)	1647 ± 162	1213 ± 77	0.690 (0.505–0.856)	<1210	0.1293

Mean ± SEM, AUROC (95% CI of the mean), p values are from ROC analysis.