TABLE 5.

Relationship Between WHS-Defined DED and Units Per Day of the Sources of Caffeine, in a Multivariate Model Including All Sources

	All (N = 70,666)
	OR (95% CI), Model 1*	P	OR (95% CI), Model 2†	P	OR (95% CI), Model 3‡	P
Coffee intake (cups/d)	0.984 (0.970–0.998)	0.03	0.987 (0.972–1.002)	0.09	1.000 (0.984–1.016)	0.98
Tea intake (cups/d)	1.027 (1.013–1.042)	<0.001	1.021 (1.006–1.036)	0.006	1.013 (0.998–1.029)	0.09
Cola intake (glass/d)	0.975 (0.928–1.024)	0.31	0.970 (0.919–1.023)	0.26	0.950 (0.898–1.004)	0.07
Energy drink intake (glass/d)	1.183 (0.950–1.471)	0.13	1.124 (0.875–1.443)	0.36	1.005 (0.758–1.333)	0.97

Bolded items indicate statistical significance (P < 0.05).

^*Model 1: corrected for age and sex alone.

^†Model 2: corrected for age, sex, body mass index, alcohol intake, smoking status, education level, and net monthly household income, full data available for 65,834 participants.

^‡Model 3: corrected for age, sex, BMI, alcohol intake, smoking status, education level, net monthly household income, and 48 comorbidities associated with dry eye; full data available for 64,924 participants.