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. 2022 Jan 26;42(2):186–193. doi: 10.1097/ICO.0000000000002979

TABLE 6.

Relationship Between WHS-Defined DED and Cups/d of Caffeinated/Decaffeinated Coffee in Coffee Drinkers Only, in a Multivariate Model Including Both

All (N = 56,332)
OR (95% CI), Model 1* P OR (95% CI), Model 2 P OR (95% CI), Model 3 P
Caffeinated coffee intake (cups/d) 0.975 (0.961–0.990) 0.001 0.981 (0.965–‡0.997) 0.02 0.995 (0.979–1.012) 0.58
Decaffeinated coffee intake (cups/d) 1.034 (1.002–1.068) 0.04 1.042 (1.007–1.077) 0.02 1.046 (1.010–1.084) 0.01

Bolded items indicate statistical significance (P < 0.05).

*

Model 1: corrected for age and sex alone.

Model 2: corrected for age, sex, body mass index, alcohol intake, smoking status, education level, and net monthly household income; full data available for 52,041 participants.

Model 3: corrected for age, sex, body mass index, alcohol intake, smoking status, education level, net monthly household income, and 48 comorbidities associated with dry eye; full data available for 51,607 participants.