Table 4.
Correlation of IgG and IgM anti-PLIN1 autoantibody titers with physical, demographical, and laboratory parameters
| IgG autoantibodies | IgM autoantibodies | |||
|---|---|---|---|---|
| r | P value | r | P value | |
| Age (years) | −0.11 | 0.66 | −0.76 | 0.08 |
| Lipodystrophy onset (years) | 0.33 | 0.20 | 0.24 | 0.70 |
| Time with lipodystrophy (years) | −0.16 | 0.52 | −0.47 | 0.34 |
| BMI (kg/m2) | 0.05 | 0.84 | −0.50 | 0.30 |
| Percent total fat | −0.29 | 0.27 | −0.71 | 0.18 |
| Glucose (mg/dL) | 0.57 | 0.011 | 0.37 | 0.47 |
| Insulin (μU/mL) | 0.73 | 0.002 | −0.22 | 0.72 |
| HbA1c (mmol/mol) | 0.17 | 0.48 | 0.23 | 0.67 |
| HOMA-IR | −0.19 | 0.49 | 0.09 | 0.90 |
| Leptin (ng/mL) | 0.45 | 0.11 | 0.48 | 0.52 |
| Triglycerides (mg/dL) | 0.51 | 0.035 | 0.01 | 0.98 |
| Total cholesterol (mg/dL) | −0.17 | 0.52 | −0.70 | 0.19 |
| HDL-cholesterol (mg/dL) | −0.50 | 0.046 | 0.20 | 0.74 |
| ALT (IU/L) | 0.42 | 0.08 | 0.34 | 0.51 |
| AST (IU/L) | 0.59 | 0.011 | −0.15 | 0.80 |
| IgG (mg/dL) | −0.20 | 0.48 | −0.86 | 0.14 |
| IgA (mg/dL) | 0.06 | 0.84 | 0.08 | 0.92 |
| IgM (mg/dL) | 0.58 | 0.029 | 0.21 | 0.80 |
| C3 (mg/dL) | −0.28 | 0.26 | 0.60 | 0.20 |
| C4 (mg/dL) | −0.40 | 0.11 | −0.40 | 0.52 |
Association analyses were performed using Pearson or Spearman test. P value <0.05 was considered statistically significant and are indicated in italics.