Table 1.

Comparison of extraction methods of CEP.

Method	Advantage	Disadvantage
Organic solvent extraction	Simple equipment, easy to implement, the most widely used.	Time-consuming, laborious and harmless.
Ultrasound-assisted extraction	Simple and time-saving, low energy consumption, wide application.	It is easy to affect the consistency of CEP yield in different batches.
Microwave-assisted extraction	The most time-saving, solvent saving.	It can induce undesirable structural modifications and is not conductive to large-scale production.
Enzyme-assisted extraction	The conditions are mild, low temperature, high efficiency and reduction of equipment corrosion.	High cost, large amount of enzyme, and is not suitable for industrial scales
Ultrasound-assisted extraction and aqueous two-phase	Advance extraction yields, environmentally-friendly, energy-saving.	Long phase separation time at aqueous two-phase step.