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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Allergy. 2022 Aug 8;78(1):192–201. doi: 10.1111/all.15457

Figure 1. SDS induces epithelial barrier dysfunction in vitro.

Figure 1.

(A) Kinetic changes in TEER in EPC2 ALI cultures exposed to serial dilutions of SDS are shown. Data are presented as mean±SEM of 3 samples and are a representative of 4 experiments. *p < 0.05 compared to the cells with no SDS. (B) EPC2 ALI cultures were exposed to SDS for 96 hrs and permeability to FITC-dextran was examined. Data are presented as mean±SEM of 4 samples. ***p < 0.0001 between the groups indicated by a horizotal line. (C) EPC2 cells were exposed to SDS for 6 hrs (for IL-33) or 72 hrs (for DSG1), and the expression of mRNA for IL-33 and DSG1 was examined by real-time RT-PCR. Data are presented as mean±SEM of 3-4 samples. *p < 0.05, **p < 0.01, ****p < 0.0001 between the groups indicated by horizontal lines.