Table 2.
Multivariable model of youth risk variables predicting cardiovascular events based on fully imputed data including 95 cardiovascular cases and 3483 non-cases in the Young Finns Study.
| Hazard Ratio | P-value | |
|---|---|---|
| Lp(a) < 30 mg/dL vs. ≥ 30 mg/dL | 1.77 (1.17–2.37) | 0.035 |
| LDL-cholesterol | 1.26 (1.06–1.47) | 0.025 |
| Body mass index | 1.25 (1.06–1.43) | 0.022 |
| Smoking (no vs. yes) | 1.58 (1.16–2.00) | 0.033 |
| Systolic blood pressure | 1.13 (0.86–1.40) | 0.36 |
Models were additionally adjusted for age and sex. LDL-cholesterol and body mass index represent average values between ages 6–18 years and are modelled as standardized continuous variables (risk ratios indicate change per one standard deviation). For LDL-cholesterol one standard deviation equals 26 mg/dL (0.66 mmol/L); for body mass index one standard deviation equals 2.4 kg/m2; for systolic blood pressure one standard deviation equals 6.4 mmHg.
Pooled estimates are based on 20 imputed datasets.