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. 2022 Nov 17;40(6):2103–2116. doi: 10.1007/s12640-022-00605-4

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Effect of Met and EGCG on levels of p53 (ng/g tissue; a), Bax (ng/g tissue; b), caspase 9 (ng/g tissue; c), caspase 3 (ng/g tissue; d), and Bcl-2 (ng/g tissue; e) in the brains of all experimental groups. Data are shown as mean ± SEM (n = 6). A single asterisk and a single ampersand (*, ^&) indicate significance at P < 0.05, and triple asterisks and triple ampersands (***, ^&&&) indicate significance at P < 0.001. A single asterisk and triple asterisks (*, ***) indicate comparisons with respect to the control group. A single ampersand and triple ampersands (^&, ^&&&) indicate comparisons with respect to the methionine group. Cont, control; EGCG, epigallocatechin-3-gallate; Met, methionine; Met + EGCG, methionine + epigallocatechin-3-gallate