TABLE 2.
Sequence similarities of L. pneumophila genes identified by signature-tagged mutagenesisa
| Mutant strain | Homologous gene | Organism | Putative function | % Identity | % Positive | Length (amino acids) | Score | E value |
|---|---|---|---|---|---|---|---|---|
| STM-1 | ccmF | Pseudomonas fluorescens | Cytochrome c biogenesis | 46 | 56 | 213 | 159 | 4e−38 |
| STM-2 | flrC | Vibrio cholera | Transcriptional activator of a two-component regulatory system that regulates flagella biosynthesis | 60 | 74 | 258 | 280 | 1e−74 |
| STM-3 | lspK | Legionella pneumophila | Type II secretion system structural protein | |||||
| STM-4 | Unknown (207 nucleotides) | |||||||
| STM-5 | aroB | Legionella pneumophila | Aromatic amino acid biosynthesis | |||||
| STM-6 | traA | Rhizobium sp. NGR234 | Protein involved in conjugal transfer | 36 | 56 | 271 | 166 | 1e−39 |
a
The values are taken from a Basic Local Alignment Search Tool for amino acid comparison (blastx program) (3). The amino acid length refers to a contiguous length of sequence similarity.