TABLE 5.
The anti-cancer effects of nine combinations of three drugs on MCF-7 cells.
| Predicted ranking | Group number | The IC50 (nM) of drug combinations | The best IC50 | |||
|---|---|---|---|---|---|---|
| Ⅰ | Ⅱ | Ⅲ | Ⅳ | |||
| 1 | Ⅲ12 | 90.43 | 31.37 | 30.88 | 42.94 | 30.88 |
| 2 | Ⅲ7 | 290.99 | 101.66 | 56.52 | 85.66 | 56.52 |
| 3 | Ⅲ18 | 102.14 | 128.37 | 88.62 | 168.34 | 88.62 |
| 62 | Ⅲ40 | 2268.13 | 535.42 | 5823.46 | 308.97 | 308.97 |
| 63 | Ⅲ43 | 640.90 | 6386.59 | 4144.85 | 598.10 | 598.10 |
| 65 | Ⅲ47 | 10584.30 | 827.17 | 18532.30 | 10219.80 | 827.17 |
| 118 | Ⅲ9 | 23145.90 | 11,675.80 | 2121.31 | 2784.08 | 2121.31 |
| 119 | Ⅲ44 | 2606.11 | 2197.47 | 1499.70 | 1523.97 | 1499.70 |
| 125 | Ⅲ41 | 6022.00 | 354825.00 | 84020.00 | 24170.00 | 6022.00 |
Note: the predicted ranking included 120 drug combinations and individual drugs themselves.